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Engulfment pathways promote programmed cell death by enhancing the unequal segregation of apoptotic potential

Components of the conserved engulfment pathways promote programmed cell death in Caenorhabditis elegans (C. elegans) through an unknown mechanism. Here we report that the phagocytic receptor CED-1 mEGF10 is required for the formation of a dorsal–ventral gradient of CED-3 caspase activity within the...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Chakraborty, Sayantan, Lambie, Eric J., Bindu, Samik, Mikeladze-Dvali, Tamara, Conradt, Barbara
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682117/
https://ncbi.nlm.nih.gov/pubmed/26657541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10126
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