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Engulfment pathways promote programmed cell death by enhancing the unequal segregation of apoptotic potential

Components of the conserved engulfment pathways promote programmed cell death in Caenorhabditis elegans (C. elegans) through an unknown mechanism. Here we report that the phagocytic receptor CED-1 mEGF10 is required for the formation of a dorsal–ventral gradient of CED-3 caspase activity within the...

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發表在:Nat Commun
Main Authors: Chakraborty, Sayantan, Lambie, Eric J., Bindu, Samik, Mikeladze-Dvali, Tamara, Conradt, Barbara
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682117/
https://ncbi.nlm.nih.gov/pubmed/26657541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10126
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