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Comprehensive Application of Time-of-flight Secondary Ion Mass Spectrometry (TOF-SIMS) for Ionic Imaging and Bio-energetic Analysis of Club Drug-induced Cognitive Deficiency

Excessive exposure to club drug (GHB) would cause cognitive dysfunction in which impaired hippocampal Ca(2+)-mediated neuroplasticity may correlate with this deficiency. However, the potential changes of in vivo Ca(2+) together with molecular machinery engaged in GHB-induced cognitive dysfunction ha...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Youn, Su-Chung, Chen, Li-You, Chiou, Ruei-Jen, Lai, Te-Jen, Liao, Wen-Chieh, Mai, Fu-Der, Chang, Hung-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682059/
https://ncbi.nlm.nih.gov/pubmed/26674573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18420
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