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Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis
TANK Binding Kinase 1 (TBK1) is a non-canonical IκB kinase that contributes to KRAS-driven lung cancer. Here we report that TBK1 plays essential roles in mammalian cell division. Specifically, levels of active phospho-TBK1 increase during mitosis and localize to centrosomes, mitotic spindles and mid...
Sparad:
| I publikationen: | Nat Commun |
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| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4682058/ https://ncbi.nlm.nih.gov/pubmed/26656453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10072 |
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