Cellular Adaptation to VEGF-Targeted Antiangiogenic Therapy Induces Evasive Resistance by Overproduction of Alternative Endothelial Cell Growth Factors in Renal Cell Carcinoma()()

Vascular endothelial growth factor (VEGF)–targeted antiangiogenic therapy significantly inhibits the growth of clear cell renal cell carcinoma (RCC). Eventually, therapy resistance develops in even the most responsive cases, but the mechanisms of resistance remain unclear. Herein, we developed two t...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Han, Kyung Seok, Raven, Peter A., Frees, Sebastian, Gust, Kilian, Fazli, Ladan, Ettinger, Susan, Hong, Sung Joon, Kollmannsberger, Cristian, Gleave, Martin E., So, Alan I.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681895/
https://ncbi.nlm.nih.gov/pubmed/26678908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.11.001
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