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Mutations and Modeling of the Chromatin Remodeler CHD8 Define an Emerging Autism Etiology

Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder with a strong but complex genetic component. Recent family based exome-sequencing strategies have identified recurrent de novo mutations at specific genes, providing strong evidence for ASD risk, but also highlighting the extreme...

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Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Barnard, Rebecca A., Pomaville, Matthew B., O'Roak, Brian J.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681771/
https://ncbi.nlm.nih.gov/pubmed/26733790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00477
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