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Recent Positive Selection Drives the Expansion of a Schizophrenia Risk Nonsynonymous Variant at SLC39A8 in Europeans

Natural selection has played important roles in optimizing complex human adaptations. However, schizophrenia poses an evolutionary paradox during human evolution, as the illness has strongly negative effects on fitness, but persists with a prevalence of ~0.5% across global populations. Recent studie...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Li, Ming, Wu, Dong-Dong, Yao, Yong-Gang, Huo, Yong-Xia, Liu, Jie-Wei, Su, Bing, Chasman, Daniel I., Chu, Audrey Y., Huang, Tao, Qi, Lu, Zheng, Yan, Luo, Xiong-Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681542/
https://ncbi.nlm.nih.gov/pubmed/26006263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbv070
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