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Determining the factors driving selective effects of new nonsynonymous mutations
The distribution of fitness effects (DFE) of new mutations plays a fundamental role in evolutionary genetics. However, the extent to which the DFE differs across species has yet to be systematically investigated. Furthermore, the biological mechanisms determining the DFE in natural populations remai...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410820/ https://ncbi.nlm.nih.gov/pubmed/28400513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619508114 |
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