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Metabolic disposition of the anti-cancer agent [(14)C]laromustine in male rats

1. Laromustine (VNP40101M, also known as Cloretazine) is a novel sulfonylhydrazine alkylating (anticancer) agent. This article describes the use of quantitative whole-body autoradiography (QWBA) and mass balance to study the tissue distribution, the excretion mass balance and pharmacokinetics after...

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Detalhes bibliográficos
Publicado no:Xenobiotica
Main Authors: Nassar, Ala F., Wisnewski, Adam, King, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681490/
https://ncbi.nlm.nih.gov/pubmed/25798740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2015.1016475
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