Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch is Required for Herpes Simplex Virus Reactivation

Herpes simplex virus (HSV) reactivation from latent neuronal infection requires stimulation of lytic gene expression from promoters associated with repressive heterochromatin. Various neuronal stresses trigger reactivation, but how these stimuli activate silenced promoters remains unknown. We show t...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Cliffe, Anna R., Arbuckle, Jesse H., L.Vogel, Jodi, Geden, Matthew J., Rothbart, Scott B., Cusack, Corey L., Strahl, Brian D., Kristie, Thomas M., Deshmukh, Mohanish
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681005/
https://ncbi.nlm.nih.gov/pubmed/26651941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.11.007
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