Nudix hydrolases degrade protein-conjugated ADP-ribose

ADP-ribosylation refers to the transfer of the ADP-ribose group from NAD(+) to target proteins post-translationally, either attached singly as mono(ADP-ribose) (MAR) or in polymeric chains as poly(ADP-ribose) (PAR). Though ADP-ribosylation is therapeutically important, investigation of this protein...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Daniels, Casey M., Thirawatananond, Puchong, Ong, Shao-En, Gabelli, Sandra B., Leung, Anthony K. L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680915/
https://ncbi.nlm.nih.gov/pubmed/26669448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18271
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