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Identifying poly(ADP-ribose)-binding proteins with photoaffinity-based proteomics

Post-translational modification of proteins with poly(ADP-ribose) (PAR) is an important component of the DNA damage response. Four PAR synthesis inhibitors have recently been approved for the treatment of breast, ovarian, and prostate cancers. Despite its clinical significance, a molecular understan...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Dasovich, Morgan, Beckett, Morgan Q., Bailey, Scott, Ong, Shao-En, Greenberg, Marc M., Leung, Anthony K. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109396/
https://ncbi.nlm.nih.gov/pubmed/33596067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c12246
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