Clinical utility of circulating tumor DNA for molecular assessment in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies. The genomic landscape of the PDAC genome features four frequently mutated genes (KRAS, CDKN2A, TP53, and SMAD4) and dozens of candidate driver genes altered at low frequency, including potential clinical targets. Ci...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Takai, Erina, Totoki, Yasushi, Nakamura, Hiromi, Morizane, Chigusa, Nara, Satoshi, Hama, Natsuko, Suzuki, Masami, Furukawa, Eisaku, Kato, Mamoru, Hayashi, Hideyuki, Kohno, Takashi, Ueno, Hideki, Shimada, Kazuaki, Okusaka, Takuji, Nakagama, Hitoshi, Shibata, Tatsuhiro, Yachida, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680882/
https://ncbi.nlm.nih.gov/pubmed/26669280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18425
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