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5-Aza-CdR can reverse gefitinib resistance caused by DAPK gene promoter methylation in lung adenocarcinoma cells

To explore the relationship between death associated protein kinase (DAPK) gene promoter methylation and gefitinib resistance in Lung adenocarcinoma cell lines. EGFR-mutation lung adenocarcinoma cell lines PC9 and the gefitinib-resistant with T790M Mutation cell lines PC9/GR were chosen as cell mode...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Clin Exp Pathol
Hauptverfasser: Yang, Bo, Yang, Zhi-Guang, Gao, Bao, Shao, Guo-Guang, Li, Guang-Hu
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680436/
https://ncbi.nlm.nih.gov/pubmed/26722491
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