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5-Aza-CdR can reverse gefitinib resistance caused by DAPK gene promoter methylation in lung adenocarcinoma cells

To explore the relationship between death associated protein kinase (DAPK) gene promoter methylation and gefitinib resistance in Lung adenocarcinoma cell lines. EGFR-mutation lung adenocarcinoma cell lines PC9 and the gefitinib-resistant with T790M Mutation cell lines PC9/GR were chosen as cell mode...

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Bibliografiske detaljer
Udgivet i:Int J Clin Exp Pathol
Main Authors: Yang, Bo, Yang, Zhi-Guang, Gao, Bao, Shao, Guo-Guang, Li, Guang-Hu
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680436/
https://ncbi.nlm.nih.gov/pubmed/26722491
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