Correlations between expression levels of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase, and efficacy of 5-fluorouracil-based chemotherapy for advanced colorectal cancer

The efficacy of 5-fluorouracil (5-FU)-based chemotherapy for colorectal cancer (CRC) widely varies among patients; therefore, it is difficult to accurately predict chemotherapeutic responses. Some recent studies have found that key enzymes in the various metabolic pathways activated by 5-FU present...

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Bibliografiske detaljer
Udgivet i:Int J Clin Exp Pathol
Main Authors: Bai, Wenqi, Wu, Yueqin, Zhang, Ping, Xi, Yanfeng
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680365/
https://ncbi.nlm.nih.gov/pubmed/26722420
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