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Effect of smoking on physical and cognitive capability in later life: a multicohort study using observational and genetic approaches

OBJECTIVES: The observed associations between smoking and functional measures at older ages are vulnerable to bias and confounding. Mendelian randomisation (MR) uses genotype as an instrumental variable to estimate unconfounded causal associations. We conducted a meta-analysis of the observational a...

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Bibliografiske detaljer
Udgivet i:BMJ Open
Main Authors: North, Teri-Louise, Palmer, Tom M, Lewis, Sarah J, Cooper, Rachel, Power, Chris, Pattie, Alison, Starr, John M, Deary, Ian J, Martin, Richard M, Aihie Sayer, Avan, Kumari, Meena, Cooper, Cyrus, Kivimaki, Mika, Kuh, Diana, Ben-Shlomo, Yoav, Day, Ian N M
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679991/
https://ncbi.nlm.nih.gov/pubmed/26671949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-008393
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