Effect of smoking on physical and cognitive capability in later life: a multicohort study using observational and genetic approaches

OBJECTIVES: The observed associations between smoking and functional measures at older ages are vulnerable to bias and confounding. Mendelian randomisation (MR) uses genotype as an instrumental variable to estimate unconfounded causal associations. We conducted a meta-analysis of the observational a...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: North, Teri-Louise, Palmer, Tom M, Lewis, Sarah J, Cooper, Rachel, Power, Chris, Pattie, Alison, Starr, John M, Deary, Ian J, Martin, Richard M, Aihie Sayer, Avan, Kumari, Meena, Cooper, Cyrus, Kivimaki, Mika, Kuh, Diana, Ben-Shlomo, Yoav, Day, Ian N M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Smoking and Tobacco
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679991/
https://ncbi.nlm.nih.gov/pubmed/26671949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-008393
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