Intramuscular Priming and Intranasal Boosting Induce Strong Genital Immunity Through Secretory IgA in Minipigs Infected with Chlamydia trachomatis

International efforts in developing a vaccine against Chlamydia trachomatis have highlighted the need for novel immunization strategies for the induction of genital immunity. In this study, we evaluated an intramuscular (IM) prime/intranasal boost vaccination strategy in a Göttingen Minipig model wi...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lorenzen, Emma, Follmann, Frank, Bøje, Sarah, Erneholm, Karin, Olsen, Anja Weinreich, Agerholm, Jørgen Steen, Jungersen, Gregers, Andersen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679855/
https://ncbi.nlm.nih.gov/pubmed/26734002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00628
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