A multi-subunit Chlamydia vaccine inducing neutralizing antibodies and strong IFN-γ(+) CMI responses protects against a genital infection in minipigs

Chlamydia is the most widespread sexually transmitted bacterial disease and a prophylactic vaccine is highly needed. Ideally, this vaccine is required to induce a combined response of Th1 cell-mediated immune (CMI) response in concert with neutralizing antibodies. Using a novel Göttingen minipig ani...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Bøje, Sarah, Olsen, Anja Weinreich, Erneholm, Karin, Agerholm, Jørgen Steen, Jungersen, Gregers, Andersen, Peter, Follmann, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748142/
https://ncbi.nlm.nih.gov/pubmed/26268662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2015.79
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