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p53 mutations increase resistance to ionizing radiation.

Mouse and human tumors of diverse origin frequently have somatically acquired mutations or rearrangements of the p53 gene, or they have lost one or both copies of the gene. Although wild-type p53 protein is believed to function as a tumor-suppressor gene, it is as yet unclear how p53 mutations lead...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lee, J M, Bernstein, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46798/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8516323/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.12.5742
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