Characterization of a Novel Integrin Binding Protein, VPS33B, Which is Important for Platelet Activation and in vivo Thrombosis and Hemostasis

BACKGROUND: Integrins are heterodimeric (α/β) membrane proteins that play fundamental roles in many biological processes, e.g. cell adhesion and spreading, which are important for platelet function and hemostasis. The molecular mechanism that regulates integrin activation is not completely understoo...

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Publicado no:Circulation
Main Authors: Xiang, Binggang, Zhang, Guoying, Ye, Shaojing, Zhang, Rui, Huang, Cai, Liu, Jun, Tao, Min, Ruan, Changgeng, Smyth, Susan S., Whiteheart, Sidney W., Li, Zhenyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679702/
https://ncbi.nlm.nih.gov/pubmed/26399659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.018361
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