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Identification of Differentially Methylated Regions in New Genes Associated with Knee Osteoarthritis

Epigenetic changes in articular chondrocytes are associated with osteoarthritis (OA) disease progression. Numerous studies have identified differentially methylated cytosines in OA tissues; however, the consequences of altered CpG methylation at single nucleotides on gene expression and phenotypes a...

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Detalhes bibliográficos
Publicado no:Gene
Main Authors: Bonin, Carolina A., Lewallen, Eric A., Baheti, Saurabh, Bradley, Elizabeth W., Stuart, Michael J., Berry, Daniel J., van Wijnen, Andre J., Westendorf, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679536/
https://ncbi.nlm.nih.gov/pubmed/26484395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2015.10.037
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