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Cardiovirus Leader proteins bind exportins: implications for virus replication and nucleocytoplasmic trafficking inhibition
Cardiovirus Leader proteins (L(X)) inhibit cellular nucleocytoplasmic trafficking by directing host kinases to phosphorylate Phe/Gly-containing nuclear pore proteins (Nups). Resolution of the Mengovirus L(M) structure bound to Ran GTPase, suggested this complex would further recruit specific exporti...
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| Publicado en: | Virology |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4679524/ https://ncbi.nlm.nih.gov/pubmed/26492198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.10.001 |
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