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Aging neural progenitors lose competence to respond to mitogenic Notch signaling

Drosophila neural stem cells (neuroblasts) are a powerful model system for investigating stem cell self-renewal, specification of temporal identity, and progressive restriction in competence. Notch signaling is a conserved cue that is an important determinant of cell fate in many contexts across ani...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Biol
Main Authors: Farnsworth, Dylan R., Bayraktar, Omer Ali, Doe, Chris Q.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679507/
https://ncbi.nlm.nih.gov/pubmed/26585279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.10.027
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