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Aging neural progenitors lose competence to respond to mitogenic Notch signaling
Drosophila neural stem cells (neuroblasts) are a powerful model system for investigating stem cell self-renewal, specification of temporal identity, and progressive restriction in competence. Notch signaling is a conserved cue that is an important determinant of cell fate in many contexts across ani...
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| Published in: | Curr Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4679507/ https://ncbi.nlm.nih.gov/pubmed/26585279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.10.027 |
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