Mucosal delivery switches the response to an adjuvanted tuberculosis vaccine from systemic T(H)1 to tissue-resident T(H)17 responses without impacting the protective efficacy(§)

Pulmonary tuberculosis (TB) remains one of the leading causes of infectious disease death despite widespread usage of the BCG vaccine. A number of new TB vaccines have moved into clinical evaluation to replace or boost the BCG vaccine including ID93+GLA-SE, an adjuvanted subunit vaccine. The vast ma...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Vaccine
Huvudupphovsmän: Orr, Mark T., Beebe, Elyse A., Hudson, Thomas, Argilla, David, Huang, Po-Wei D., Reese, Valerie A., Fox, Christopher B., Reed, Steven G., Coler, Rhea N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679420/
https://ncbi.nlm.nih.gov/pubmed/26541135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.10.115
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk