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A Dual TLR Agonist Adjuvant Enhances the Immunogenicity and Protective Efficacy of the Tuberculosis Vaccine Antigen ID93

With over eight million cases of tuberculosis each year there is a pressing need for the development of new vaccines against Mycobacterium tuberculosis. Subunit vaccines consisting of recombinant proteins are an attractive vaccine approach due to their inherent safety compared to attenuated live vac...

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Detalhes bibliográficos
Main Authors: Orr, Mark T., Beebe, Elyse A., Hudson, Thomas E., Moon, James J., Fox, Christopher B., Reed, Steven G., Coler, Rhea N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880254/
https://ncbi.nlm.nih.gov/pubmed/24404140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083884
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