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RNAP II Processivity is a Limiting Step for HIV-1 Transcription Independent of Orientation to and Activity of Endogenous Neighboring Promoters

Since HIV-1 has a propensity to integrate into actively expressed genes, transcriptional interference from neighboring host promoters has been proposed to contribute to the establishment and maintenance HIV-1 latency. To gain insights into how endogenous promoters influence HIV-1 transcription we ut...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Michaels, Katarzyna Kaczmarek, Wolschendorf, Frank, Schiralli Lester, Gillian M., Natarajan, Malini, Kutsch, Olaf, Henderson, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679410/
https://ncbi.nlm.nih.gov/pubmed/26379089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.08.027
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