uPA Attenuated LPS-induced Inflammatory Osteoclastogenesis through the Plasmin/PAR-1/Ca(2+)/CaMKK/AMPK Axis

Chronic inflammatory diseases, such as rheumatoid arthritis and periodontitis-caused bone destruction, results from an increase of bone-resorbing osteoclasts (OCs) induced by inflammation. However, the detailed mechanisms underlying this disorder remain unclear. We herein investigated that the effec...

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Библиографические подробности
Опубликовано в: :Int J Biol Sci
Главные авторы: Kanno, Yosuke, Ishisaki, Akira, Kawashita, Eri, Kuretake, Hiromi, Ikeda, Kanako, Matsuo, Osamu
Формат: Artigo
Язык:Inglês
Опубликовано: Ivyspring International Publisher 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679399/
https://ncbi.nlm.nih.gov/pubmed/26722218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.12690
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