Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors

Affibody molecules are small (7 kDa), non-immunoglobulin scaffold proteins with a potential as targeting agents for radionuclide imaging of cancer. However, high renal re-absorption of Affibody molecules prevents their use for radionuclide therapy with residualizing radiometals. We hypothesized that...

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Detalles Bibliográficos
Publicado en:Theranostics
Main Authors: Honarvar, Hadis, Westerlund, Kristina, Altai, Mohamed, Sandström, Mattias, Orlova, Anna, Tolmachev, Vladimir, Karlström, Amelie Eriksson
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679357/
https://ncbi.nlm.nih.gov/pubmed/26722376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.12766
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