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Super-enhancers: Asset management in immune cell genomes

Super-enhancers (SEs) are regions of the genome consisting of clusters of regulatory elements bound with very high amounts of transcription factors, and this architecture appears to be the hallmark of genes and noncoding RNAs linked with cell identity. Recent studies have identified SEs in CD4(+) T...

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Detalles Bibliográficos
Publicado en:Trends Immunol
Autores principales: Witte, Steven, O’Shea, John J., Vahedi, Golnaz
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679291/
https://ncbi.nlm.nih.gov/pubmed/26277449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2015.07.005
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