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Large sample inference for a win ratio analysis of a composite outcome based on prioritized components

Composite outcomes are common in clinical trials, especially for multiple time-to-event outcomes (endpoints). The standard approach that uses the time to the first outcome event has important limitations. Several alternative approaches have been proposed to compare treatment versus control, includin...

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Detalhes bibliográficos
Publicado no:Biostatistics
Main Authors: Bebu, Ionut, Lachin, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679075/
https://ncbi.nlm.nih.gov/pubmed/26353896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxv032
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