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Properties of Composite Time-to-First-Event versus Joint Marginal Analyses of Multiple Outcomes

Many clinical studies (e.g., cardiovascular outcome trials) investigate the effect of an intervention on multiple event-time outcomes. The most common method of analysis is a so-called ”composite” analysis of a composite outcome defined as the time to the first component event. Other approaches have...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Bebu, Ionut, Lachin, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615937/
https://ncbi.nlm.nih.gov/pubmed/29956365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7849
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