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Inhibition of host cell translation elongation by Legionella pneumophila blocks the host cell unfolded protein response

Cells of the innate immune system recognize bacterial pathogens by detecting common microbial patterns as well as pathogen-specific activities. One system that responds to these stimuli is the IRE1 branch of the unfolded protein response (UPR), a sensor of endoplasmic reticulum (ER) stress. Activati...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Hempstead, Andrew D., Isberg, Ralph R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679008/
https://ncbi.nlm.nih.gov/pubmed/26598709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508716112
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