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Reverse Electron Transfer Completes the Catalytic Cycle in a 2,3,5-Trifluorotyrosine-Substituted Ribonucleotide Reductase
[Image: see text] Escherichia coli class Ia ribonucleotide reductase is composed of two subunits (α and β), which form an α2β2 complex that catalyzes the conversion of nucleoside 5′-diphosphates to deoxynucleotides (dNDPs). β2 contains the essential tyrosyl radical (Y(122)(•)) that generates a thiyl...
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| Vydáno v: | J Am Chem Soc |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical Society
2015
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4678968/ https://ncbi.nlm.nih.gov/pubmed/26492582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b09189 |
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