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Discover hidden splicing variations by mapping personal transcriptomes to personal genomes

RNA-seq has become a popular technology for studying genetic variation of pre-mRNA alternative splicing. Commonly used RNA-seq aligners rely on the consensus splice site dinucleotide motifs to map reads across splice junctions. Consequently, genomic variants that create novel splice site dinucleotid...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Stein, Shayna, Lu, Zhi-xiang, Bahrami-Samani, Emad, Park, Juw Won, Xing, Yi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678817/
https://ncbi.nlm.nih.gov/pubmed/26578562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1099
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