GLiMMPS: robust statistical model for regulatory variation of alternative splicing using RNA-seq data

To characterize the genetic variation of alternative splicing, we develop GLiMMPS, a robust statistical method for detecting splicing quantitative trait loci (sQTLs) from RNA-seq data. GLiMMPS takes into account the individual variation in sequencing coverage and the noise prevalent in RNA-seq data....

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Detalhes bibliográficos
Main Authors: Zhao, Keyan, Lu, Zhi-xiang, Park, Juw Won, Zhou, Qing, Xing, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054007/
https://ncbi.nlm.nih.gov/pubmed/23876401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-7-r74
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