Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment

BACKGROUND: Tasquinimod (a quinoline-3-carboxyamide) is a small molecule immunotherapy with demonstrated effects on the tumor microenvironment (TME) involving immunomodulation, anti-angiogenesis and inhibition of metastasis. A target molecule of tasquinimod is the inflammatory protein S100A9 which h...

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Dettagli Bibliografici
Pubblicato in:J Immunother Cancer
Autori principali: Olsson, Anders, Nakhlé, Jessica, Sundstedt, Anette, Plas, Pascale, Bauchet, Anne-Laure, Pierron, Valérie, Bruetschy, Luce, Deronic, Adnan, Törngren, Marie, Liberg, David, Schmidlin, Fabien, Leanderson, Tomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678646/
https://ncbi.nlm.nih.gov/pubmed/26673090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-015-0098-5
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