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Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment
BACKGROUND: Tasquinimod (a quinoline-3-carboxyamide) is a small molecule immunotherapy with demonstrated effects on the tumor microenvironment (TME) involving immunomodulation, anti-angiogenesis and inhibition of metastasis. A target molecule of tasquinimod is the inflammatory protein S100A9 which h...
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| Pubblicato in: | J Immunother Cancer |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4678646/ https://ncbi.nlm.nih.gov/pubmed/26673090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-015-0098-5 |
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