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Spontaneous Formation of RNA Strands, Peptidyl RNA, and Cofactors

How the biochemical machinery evolved from simple precursors is an open question. Here we show that ribonucleotides and amino acids condense to peptidyl RNAs in the absence of enzymes under conditions established for genetic copying. Untemplated formation of RNA strands that can encode genetic infor...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Jauker, Mario, Griesser, Helmut, Richert, Clemens
Format: Artigo
Sprog:Inglês
Udgivet: WILEY-VCH Verlag 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678511/
https://ncbi.nlm.nih.gov/pubmed/26435376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201506593
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