In vivo molecular neuroimaging of glucose utilization and its association with fibrillar amyloid-β load in aged APPPS1-21 mice

INTRODUCTION: Radioligand imaging is a powerful in vivo method to assess the molecular basis of Alzheimer’s Disease. We therefore aimed to visualize the pathological deposition of fibrillar amyloid-β and neuronal dysfunction in aged double transgenic mice. METHODS: Using non-invasive positron emissi...

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Publicat a:Alzheimers Res Ther
Autors principals: Waldron, Ann-Marie, Wintmolders, Cindy, Bottelbergs, Astrid, Kelley, Jonathan B., Schmidt, Mark E., Stroobants, Sigrid, Langlois, Xavier, Staelens, Steven
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678474/
https://ncbi.nlm.nih.gov/pubmed/26666747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-015-0158-6
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