In Vivo Amyloid-β Imaging in the APPPS1–21 Transgenic Mouse Model with a (89)Zr-Labeled Monoclonal Antibody

Introduction: The accumulation of amyloid-β is a pathological hallmark of Alzheimer’s disease and is a target for molecular imaging probes to aid in diagnosis and disease monitoring. This study evaluated the feasibility of using a radiolabeled monoclonal anti-amyloid-β antibody (JRF/AβN/25) to non-i...

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Bibliographic Details
Published in:Front Aging Neurosci
Main Authors: Waldron, Ann-Marie, Fissers, Jens, Van Eetveldt, Annemie, Van Broeck, Bianca, Mercken, Marc, Pemberton, Darrel J., Van Der Veken, Pieter, Augustyns, Koen, Joossens, Jurgen, Stroobants, Sigrid, Dedeurwaerdere, Stefanie, Wyffels, Leonie, Staelens, Steven
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815004/
https://ncbi.nlm.nih.gov/pubmed/27064204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00067
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