Effects of glycemic control on glucose utilization and mitochondrial respiration during resuscitated murine septic shock

BACKGROUND: This study aims to test the hypothesis whether lowering glycemia improves mitochondrial function and thereby attenuates apoptotic cell death during resuscitated murine septic shock. METHODS: Immediately and 6 h after cecal ligation and puncture (CLP), mice randomly received either vehicl...

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Bibliographic Details
Published in:Intensive Care Med Exp
Main Authors: Vogt, Josef A, Wachter, Ulrich, Wagner, Katja, Calzia, Enrico, Gröger, Michael, Weber, Sandra, Stahl, Bettina, Georgieff, Michael, Asfar, Pierre, Fontaine, Eric, Radermacher, Peter, Leverve, Xavier M, Wagner, Florian
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678133/
https://ncbi.nlm.nih.gov/pubmed/26266919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2197-425X-2-19
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