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In vitro and in vivo antitumor activity of gemcitabine loaded thermosensitive liposomal nanoparticles and mild hyperthermia in pancreatic cancer

The study was designed to explore the feasibility of increasing the delivery of gemcitabine-HCL (Gem), a poor membrane permeable and short half-life drug, through PEGylated thermosensitive liposomal nanoparticles (TSLnps) delivery system followed by mild hyperthermia (mTH) at 42°C. In vitro release...

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Detalhes bibliográficos
Publicado no:Int J Adv Res (Indore)
Main Authors: Affram, Kevin, Udofot, Ofonime, Cat, Anna, Agyare, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677791/
https://ncbi.nlm.nih.gov/pubmed/26677454
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