Genome-Wide Analysis Reveals Selective Modulation of microRNAs and mRNAs by Histone Deacetylase Inhibitor in B Cells Induced to Undergo Class-Switch DNA Recombination and Plasma Cell Differentiation

As we have suggested, epigenetic factors, such as microRNAs (miRNAs), can interact with genetic programs to regulate B cell functions, thereby informing antibody and autoantibody responses. We have shown that histone deacetylase (HDAC) inhibitors (HDI) inhibit the differentiation events critical to...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Shen, Tian, Sanchez, Helia N., Zan, Hong, Casali, Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677488/
https://ncbi.nlm.nih.gov/pubmed/26697020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00627
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