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Optimization of the fabrication of novel stealth PLA-based nanoparticles by dispersion polymerization using D-optimal mixture design
PURPOSE: Nanoparticle size is important in drug delivery. Clearance of nanoparticles by cells of the reticuloendothelial system has been reported to increase with increase in particle size. Further, nanoparticles should be small enough to avoid lung or spleen filtering effects. Endocytosis and accum...
Gardado en:
| Publicado en: | Drug Dev Ind Pharm |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4677483/ https://ncbi.nlm.nih.gov/pubmed/24059281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03639045.2013.838578 |
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