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Optimization of the fabrication of novel stealth PLA-based nanoparticles by dispersion polymerization using D-optimal mixture design

PURPOSE: Nanoparticle size is important in drug delivery. Clearance of nanoparticles by cells of the reticuloendothelial system has been reported to increase with increase in particle size. Further, nanoparticles should be small enough to avoid lung or spleen filtering effects. Endocytosis and accum...

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Detalhes bibliográficos
Publicado no:Drug Dev Ind Pharm
Main Authors: Adesina, Simeon K., Wight, Scott A., Akala, Emmanuel O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677483/
https://ncbi.nlm.nih.gov/pubmed/24059281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03639045.2013.838578
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