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AIDing cancer treatment: Reducing AID activity via HSP90 inhibition
The activation induced deaminase (AID) catalyses the two key events underlying humoral adaptive immunity: class switch recombination and somatic hypermutation of antibody genes in B lymphocytes. AID accomplishes this task by directly deaminating cytosines within the genomic immunoglobulin locus, the...
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| Publicado no: | Eur J Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4677455/ https://ncbi.nlm.nih.gov/pubmed/26151367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545832 |
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