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A novel single-chain antibody redirects adenovirus to IL13Rα2-expressing brain tumors
The generation of a targeting agent that strictly binds to IL13Rα2 will significantly expand the therapeutic potential for the treatment of IL13Rα2-expressing cancers. In order to fulfill this goal, we generated a single-chain antibody (scFv47) from our parental IL13Rα2 monoclonal antibody and teste...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4677343/ https://ncbi.nlm.nih.gov/pubmed/26656559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18133 |
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