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Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid.

Cells of the yeast Saccharomyces cerevisiae are delayed in the G2 phase of the cell cycle following chromosomal DNA damage. This arrest is RAD9-dependent and suggests a signaling mechanism(s) between chromosomal lesions and cell cycling. We examined the global nature of growth inhibition caused by a...

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Main Authors: Bennett, C B, Lewis, A L, Baldwin, K K, Resnick, M A
格式: Artigo
語言:Inglês
出版: 1993
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC46771/
https://ncbi.nlm.nih.gov/pubmed/8516308
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